DYSLIPIDEMIA PROFILE OF TYPE 2 DIABETIC PATIENTS ATTENDING STATE HOSPITAL IN ILARO, NIGERIA

Dorcas Wusu Adedoja; A. Yusuf AbduFattah; Idowu Kazeem Mutiu

Dorcas Wusu Adedoja Department of Biochemistry, Lagos State University, Faculty of Science,Lagos, Nigeria
A. Yusuf AbduFattah Department of Biochemistry, Lagos State University, Faculty of Science, Lagos, Nigeria
Idowu Kazeem Mutiu Department of Biochemistry, Lagos State University, Faculty of Science, Lagos, Nigeria

Keywords: Dyslipidaemia, HDL-cholesterol, phospholipids, hypercholesterolemia, diabetes, LDL-cholesterol

Abstract

Dyslipidemia is a common feature of diabetic patients, and this condition is a risk factor for the development of cardiovascular diseases. The dyslipidemia patterns were investigated in diabetic patients undergoing medical and dietary treatment. Diabetic patients attending the Diabetes Clinic in State Hospital, Ilaro, Nigeria were recruited into the study after their informed consent. Both anthropometric and biochemical analysis was conducted. Both diabetic normotensive (DBN) and diabetic hypertensive (DBH) subjects had significantly reduced (p < 0.05) plasma phospholipids and high density lipoprotein cholesterol (HDL-C), as well as significantly increased (p < 0.05) concentration of plasma glucose and low density lipoprotein cholesterol (LDL-C) compared to the non-diabetic subjects. Atherogenic indices (LDL-C/HDL-C and TG/HDL-C) were also significantly elevated (p < 0.05) in the diabetic subjects compared to the other groups. This study suggests that dyslipidemia occurred in these diabetic patients due to complications from diabetes mellitus, and this may predispose them to cardivascular diseases like atherosclerosis.